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Hi! I’m Jiachen Chen, an incoming tenure-track Assistant Professor in the Department of Bioinformatics and Biostatistics at the University of Louisville. I am an NIA F99/K00 Fellow. I completed my PhD in Biostatistics at the Boston University School of Public Health in 2026, advised by Dr. Kathryn Lunetta and Dr. Joanne Murabito. My research lies at the intersection of multi-omics integration, aging, and statistical machine learning, with a focus on uncovering the molecular mechanisms underlying frailty and cognitive decline.

Before joining BU, I completed my M.S. in Biostatistics at Yale in 2020, where I worked on clinical trial design and developed the swdpwr software for power calculations in stepped wedge cluster randomized trials. I also hold dual bachelor’s degrees in Mathematics and Finance from Tianjin University and Nankai University in 2018.

My recent work involves developing interpretable AI/ML architectures and statistical network models to integrate proteomics and immune cell data with cognitive aging phenotypes. Leveraging large-scale cohort studies such as the Framingham Heart Study and UK Biobank, I aim to identify shared biological pathways linking chronic inflammation, physical frailty, and Alzheimer’s Disease.

This site showcases my research, publications, and academic journey.